Regenerative Dermal Fillers: The Future of Natural Rejuvenation
- Apex Aesthetics

- Aug 25
- 4 min read
The world of aesthetics is evolving. Patients want to look refreshed and youthful, but they also want results that look natural, not “done.” That’s where regenerative dermal fillers and biostimulatory treatments come in. These treatments work by stimulating your body’s own collagen and elastin production for results that unfold gradually and last longer.
At Apex Aesthetics and Wellness in Palm Beach Gardens, Jason Kwiatkowski, PA-C, specializes in treatments like Radiesse, Sculptra, and PRP/PRF, helping patients achieve subtle, rejuvenated results without the risk of looking overfilled. Let’s break down how each of these treatments works, their unique benefits, and who they’re best suited for.
How Is Radiesse A Regenerative Dermal Filler?
The Science Behind It
Radiesse is made of calcium hydroxylapatite (CaHA) microspheres suspended in a gel carrier. When injected, it provides immediate volume correction, while also stimulating collagen production over time.

Applications
Restoring volume in the cheeks and jawline
Smoothing deeper wrinkles and folds (nasolabial folds, marionette lines)
Hand rejuvenation (to restore youthful volume in aging hands)
Hyperdiluted Radiesse for the Neck
One of Radiesse’s most innovative applications is hyperdilution. When Radiesse is mixed with saline and lidocaine, it can be used in thinner areas like the neck, chest, and décolleté to improve skin quality, firmness, and elasticity by stimulating collagen.
Results
Immediate volume with Radiesse
Long-term skin tightening and smoothing
Results can last 12–18 months, depending on the area treated
How Is Sculptra A Regenerative Dermal Filler?
The Science Behind It
Sculptra is made of poly-L-lactic acid (PLLA), a biocompatible synthetic material that has been safely used in medicine for decades (think dissolvable sutures). Unlike traditional dermal fillers, Sculptra does not provide immediate volume. Instead, it works gradually, stimulating collagen production for natural, long-lasting rejuvenation.

Applications
Restoring youthful contours in the midface and temples
Improving skin laxity and texture
Treating volume loss without the “puffy” look
Subtle lifting and firming over time
Results
No instant volume, results build gradually over 3–6 months
Lasts up to 2 years with proper maintenance
Ideal for patients in their 30s–50s who want to age gracefully and prevent deep wrinkles before they set in
Radiesse vs. Sculptra: Which Is Right for Me?
The Key Differences
Radiesse → Adds immediate volume + collagen stimulation (best for those who want both instant and long-term results)
Sculptra → Stimulates collagen only, with no initial volume (best for those seeking subtle, progressive rejuvenation without added fullness)
This distinction is important in today’s climate, where terms like “pillow face” and “overfilled look” dominate online discussions. Both treatments allow patients to achieve rejuvenation without obvious volume, especially when guided by an experienced injector. It’s not the injectable that is giving this look. . . It’s the injector. Make sure you choose the right one!
What About PRP/PRF?
The Science Behind It
PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) are regenerative treatments derived from your own blood. Here’s how they work:
A small amount of blood is drawn.
The blood is spun in a centrifuge to separate the platelets.
The concentrated platelets are reinjected into the skin, scalp, or target area.
PRP vs. PRF
PRP → Processed with an additive to keep it liquid, with growth factors lasting up to 24 hours.
PRF → No additives; forms a fibrin matrix that slowly releases growth factors for up to 2 weeks.
Applications
Skin rejuvenation
Hair restoration (stimulating follicles for regrowth)
Tear troughs and under-eye rejuvenation

Results
Smoother, healthier skin
Improved texture, tone, and glow
Natural regeneration with no foreign substances
When Should I Start Considering Regenerative Fillers?
The Sooner, The Better
Regenerative fillers like Sculptra and Radiesse work best when started early, ideally in your 30s or early 40s, before deep wrinkles and significant volume loss set in. By stimulating collagen while your skin is still relatively healthy, these treatments help you age more gracefully and prevent the need for more aggressive correction later.
Why Jason’s Approach Makes the Difference
At Apex Aesthetics, Jason approaches every dermal filler, whether HA, Radiesse, Sculptra, or PRP/PRF, as a prescription. That means he considers your age, bone structure, skin health, lifestyle, and aesthetic goals before recommending the right treatment.
And here’s the key: Jason will tell you the truth. If you come in wanting only Sculptra because you’re afraid of “filler face,” but your features would benefit from a small amount of volume, Jason will guide you honestly, always prioritizing natural, undetectable results.
Regeneration Over Augmentation
In a world hyper-focused on avoiding the dreaded “pillow face,” regenerative fillers offer a refreshing alternative. By working with your body’s natural processes, treatments like Radiesse,
Sculptra, PRP/PRF provide gradual, subtle, and long-lasting rejuvenation that keeps you looking like you, just refreshed, confident, and youthful.

Ready to explore regenerative fillers? Schedule a consultation with Jason at Apex Aesthetics and Wellness in Palm Beach Gardens today to see which treatment is right for you.




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